Email: rafal.holubowicz@pwr.edu.pl

Unit: Faculty of Chemistry » Department of Biochemistry, Molecular Biology and Biotechnology

ul. Gdańska 7/9, 50-344 Wrocław
building F-4, room C-18
phone +48 71 320 6334

Office hours

• Monday 9 am - 11 am
• Tuesday 9 am - 11 am

Additional remote consultations arranged via e-mail.

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Research fields

• Biochemistry; molecular biology; structural biology; protein structure and function; analytical ultracentrifugation; biomineralization.

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Recent publications

2020

• Porębska A., Różycka M., Hołubowicz R., Ożyhar A., Dobryszycki P., (2020) Functional derivatives of human dentin matrix protein 1 modulate morphology of calcium carbonate crystals. FASEB Journal, 2020, 34(5), pp. 6147-6165, URL

2019

• Więch A., Rowińska-Żyrek M., Wątły J., Czarnota A., Hołubowicz R., Szewczuk Z., Ożyhar A., Orłowski M., (2018) The intrinsically disordered C-terminal F domain of the ecdysteroid receptor from Aedes aegypti exhibits metal ion-binding ability, Journal of Steroid Biochemistry and Molecular Biology, 186, pp. 42-55, URL

2018

• Wycisk K., Tarczewska A., Kaus-Drobek M., Dadlez M., Hołubowicz R., Pietras Z., Dziembowski A., Taube M., Kozak M., Orłowski M., Ożyhar A., (2018) Intrinsically disordered N-terminal domain of the Helicoverpa armigera Ultraspiracle stabilizes the dimeric form via a scorpion-like structure, Journal of Steroid Biochemistry and Molecular Biology, 183, pp. 167-183, URL

2017

• Hołubowicz R., Wojtas M.A., Taube M., Kozak M., Ożyhar A., Dobryszycki P., (2017) Effect of calcium ions on structure and stability of the C1q-like domain of otolin-1 from human and zebrafish. FEBS Journal, 284(24), pp. 4278-4297, URL
• Poznar M., Hołubowicz R., Wojtas M.A., Gapiński J., Banachowicz E., Patkowski A., Ożyhar A., Dobryszycki P. (2017) Structural properties of the intrinsically disordered, multiple calcium ion-binding otolith matrix macromolecule-64 (OMM-64). Biochimica et Biophysica Acta-Proteins and Proteomics, 1865 (11A), pp. 1358-1371, URL
• Wiśniewski J., Piróg M., Hołubowicz R., Dobryszycki P., McCubrey J.A., Rakus D., Gizak A. (2017) Dimeric and tetrameric forms of muscle fructose-1,6-bisphosphatase play different roles in the cell. Oncotarget, 8(70), pp. 115420-115433, URL

2016

• Kolonko M., Ożga K., Hołubowicz R., Taube M., Kozak M., Ożyhar A., Greb-Markiewicz B., (2016) Intrinsic disorder of the C-terminal domain of drosophila methoprene-tolerant protein, PLOS One, 11(9), e0162950, URL
• Wieczorek E., Kędracka-Krok S., Sołtys K., Jankowska U., Hołubowicz R., Seliga J., Ożyhar A., (2016) Is transthyretin a regulator of Ubc9 SUMOylation? PLOS One, 11(8), e0160536, URL

2015

• Wojtas M.A., Hołubowicz R., Poznar M., Maciejewska M., Ożyhar A., Dobryszycki P. (2015) Calcium ion binding properties and the effect of phosphorylation on the intrinsically disordered Starmaker protein. Biochemistry, 54(42), pp. 6525-6534, URL
• Hołubowicz R., Porębska A.M., Poznar M., Różycka M.O., Dobryszycki P. (2015) Biomineralizacja - kontrolowana przez białka precyzja kształtu, struktury i właściwości. Postępy Biochemii, 61(4), pp. 364-380, URL

Publications in DONA database